XBridge BEH C18 XP Column, 130Å, 2.5 µm, 2.1 mm X 150 mm, 3/pkg

The Waters XBridge BEH C18 HPLC/UHPLC column 150x2.1mm, 2.5µm, is based on an octadecylsilyl phase (other designations: ODS, RP-18, C18) on BEH hybrid particles and is designed for reversed-phase chromatography. The hybrid matrix is designed for very wide pH flexibility, high temperature stability and robust method development. In practice, the Waters XBridge BEH C18 is suitable, for example, for universal RP-HPLC, active pharmaceutical ingredient analysis, LC-MS methods, high-pH method development and method transfer.

Features and Benefits

• BEH hybrid particles for pH 1–12
• High temperature and pressure stability
• Particle sizes ranging from 2.5 to 10 µm
• Scalable from UHPLC to preparative chromatography
• Phases for small molecules and biomolecules

Additional Information

XBridge columns use ethylene-bridged hybrid particles in which organic bridges are incorporated into the inorganic backbone. This material architecture expands the usable pH range compared to conventional silica and enables robust methods even in the strongly alkaline range. The product family includes reverse-phase, shield, and phenyl-selective columns, as well as HILIC and amide-phase columns and wide-pore materials for peptides, proteins, glycans, and oligonucleotides. Identical chemistries across different particle sizes facilitate transfer between HPLC, UHPLC, and preparative formats.

Legal Information

XBridge is a registered trademark of Waters Corporation, Milford, Massachusetts, USA.