Macherey-Nagel / Nucleodur

Nucleodur

Nucleodur^® are high purity silica phases, manufactured by Macherey-Nagel for various (U)HPLC applications. Nucleodur^® is a fully synthetical type B silica offering highly advanced physical properties: totally spherical particle shape, outstanding surface microstructure, high pressure stability and low metal content. The columns are available in many different modifications, covering a wide selectivity range.

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VP 250/32 NUCLEODUR PolarTec, 5 µm

MN-762223.320

Product Type: HPLC Column Length: 250 mm Internal Diameter: 32 mm Particle Size: 5 µm Pore Size: 110 Å Chemistry: C18 (RP-18, ODS, Octadecyl), C18 polar embedded USP Class: L1, L60 Manufacturer: Macherey-Nagel Delivery Time: please inquire Endcapping: endcapped Carbon Load: 17.0 % Bet Surface Area [m2/g]: 340.0 Mode of Separation: Reversed Phase Chromatography (RP) Matrix: Silica Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 9.0 Pressure Stability: 600 bar Technology: HPLC Temperature Maximum [°C]: 60

VP 150/40 NUCLEODUR PolarTec, 5 µm

MN-762222.400

Product Type: HPLC Column Length: 150 mm Internal Diameter: 40 mm Particle Size: 5 µm Pore Size: 110 Å Chemistry: C18 (RP-18, ODS, Octadecyl), C18 polar embedded USP Class: L1, L60 Manufacturer: Macherey-Nagel Delivery Time: please inquire Endcapping: endcapped Carbon Load: 17.0 % Bet Surface Area [m2/g]: 340.0 Mode of Separation: Reversed Phase Chromatography (RP) Matrix: Silica Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 9.0 Pressure Stability: 600 bar Technology: HPLC Temperature Maximum [°C]: 60

VP 50/21 NUCLEODUR PolarTec, 5 µm

MN-762220.210

Product Type: HPLC Column Length: 50 mm Internal Diameter: 21 mm Particle Size: 5 µm Pore Size: 110 Å Chemistry: C18 (RP-18, ODS, Octadecyl), C18 polar embedded USP Class: L1, L60 Manufacturer: Macherey-Nagel Delivery Time: please inquire Endcapping: endcapped Carbon Load: 17.0 % Bet Surface Area [m2/g]: 340.0 Mode of Separation: Reversed Phase Chromatography (RP) Matrix: Silica Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 9.0 Pressure Stability: 600 bar Technology: HPLC Temperature Maximum [°C]: 60

VP 15/32 NUCLEODUR PFP

MN-762216.320

Product Type: HPLC Column Length: 15 mm Internal Diameter: 32 mm Pore Size: 110 Å Chemistry: PFP (Fluorophenyl Propyl) USP Class: L43 Manufacturer: Macherey-Nagel Delivery Time: please inquire Endcapping: endcapped Carbon Load: 8.0 % Bet Surface Area [m2/g]: 340.0 Mode of Separation: Reversed Phase Chromatography (RP) Matrix: Silica Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 9.0 Pressure Stability: 600 bar Technology: HPLC

VarioPrep HPLC guard column cartridge VP 10/8 NUCLEODUR PFP Length: 10 mm, ID: 8 mm pack of 2 - compatible with VarioPrep HPLC column with ID: 8 mm or ID: 10 mm - requires VP guard column holder 8 mm (p/n 718251)

MN-762214.80

Product Type: HPLC Column Length: 10 mm Internal Diameter: 8.0 mm Pore Size: 110 Å Chemistry: PFP (Fluorophenyl Propyl) USP Class: L43 Manufacturer: Macherey-Nagel Delivery Time: please inquire Endcapping: endcapped Carbon Load: 8.0 % Bet Surface Area [m2/g]: 340.0 Mode of Separation: Reversed Phase Chromatography (RP) Matrix: Silica Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 9.0 Pressure Stability: 600 bar Technology: HPLC

Vario PrepHPLC guard column cartridge (short) VP 10/16 NUCLEODUR PFP length: 10 mm, ID: 16 mm pack of 2 - compatible with VarioPrep HPLC column with ID: 16 mm or ID: 21 mm - requires VP guard column holder 16 mm (short version, REF: 718256)

MN-762214.160

Product Type: HPLC Column Length: 10 mm Internal Diameter: 16 mm Pore Size: 110 Å Chemistry: PFP (Fluorophenyl Propyl) USP Class: L43 Manufacturer: Macherey-Nagel Delivery Time: please inquire Endcapping: endcapped Carbon Load: 8.0 % Bet Surface Area [m2/g]: 340.0 Mode of Separation: Reversed Phase Chromatography (RP) Matrix: Silica Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 9.0 Pressure Stability: 600 bar Technology: HPLC

VP 250/40 NUCLEODUR PFP, 5 µm

MN-762213.400

Product Type: HPLC Column Length: 250 mm Internal Diameter: 40 mm Particle Size: 5 µm Pore Size: 110 Å Chemistry: PFP (Fluorophenyl Propyl) USP Class: L43 Manufacturer: Macherey-Nagel Delivery Time: please inquire Endcapping: endcapped Carbon Load: 8.0 % Bet Surface Area [m2/g]: 340.0 Mode of Separation: Reversed Phase Chromatography (RP) Matrix: Silica Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 9.0 Pressure Stability: 600 bar Technology: HPLC

VP 250/32 NUCLEODUR PFP, 5 µm

MN-762213.320

Product Type: HPLC Column Length: 250 mm Internal Diameter: 32 mm Particle Size: 5 µm Pore Size: 110 Å Chemistry: PFP (Fluorophenyl Propyl) USP Class: L43 Manufacturer: Macherey-Nagel Delivery Time: please inquire Endcapping: endcapped Carbon Load: 8.0 % Bet Surface Area [m2/g]: 340.0 Mode of Separation: Reversed Phase Chromatography (RP) Matrix: Silica Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 9.0 Pressure Stability: 600 bar Technology: HPLC

VarioPrep HPLC column VP 250/21 NUCLEODUR PFP, 5 µm *** with adjustable Endfitting *** length: 250 mm, ID: 21 mm pack of 1

MN-762213.210

Product Type: HPLC Column Length: 250 mm Internal Diameter: 21 mm Particle Size: 5 µm Pore Size: 110 Å Chemistry: PFP (Fluorophenyl Propyl) USP Class: L43 Manufacturer: Macherey-Nagel Delivery Time: please inquire Endcapping: endcapped Carbon Load: 8.0 % Bet Surface Area [m2/g]: 340.0 Mode of Separation: Reversed Phase Chromatography (RP) Matrix: Silica Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 9.0 Pressure Stability: 600 bar Technology: HPLC

VarioPrep HPLC column VP 250/10 NUCLEODUR PFP, 5 µm *** with adjustable Endfitting *** length: 250 mm, ID: 10 mm pack of 1

MN-762213.100

Product Type: HPLC Column Length: 250 mm Internal Diameter: 10 mm Particle Size: 5 µm Pore Size: 110 Å Chemistry: PFP (Fluorophenyl Propyl) USP Class: L43 Manufacturer: Macherey-Nagel Delivery Time: please inquire Endcapping: endcapped Carbon Load: 8.0 % Bet Surface Area [m2/g]: 340.0 Mode of Separation: Reversed Phase Chromatography (RP) Matrix: Silica Particle Morphology: spherical, fully porous pH Minimum: 1.0 pH Maximum: 9.0 Pressure Stability: 600 bar Technology: HPLC

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Technical Data

Phase-Name	Modification	Particle Size	Pore Size	End-capping	C-Content	USP	Surface	pH-Range	Tmax
Nucleodur^® C₁₈ Isis	C₁₈	1.8, 3, 5 µm	110 Å	+	20%	L1	340 m²/g	1.0‒10.0	N/A
Nucleodur^® C₁₈ Gravity	C₁₈	1.8, 3, 5 µm	110 Å	+	18%	L1	340 m²/g	1.0‒11.0	N/A
Nucleodur^® C₁₈ Gravity-SB	C₁₈	1.8, 3, 5 µm	110 Å	+	13%	L1	340 m²/g	1.0‒9.0	N/A
Nucleodur^® C₁₈ Pyramid	C₁₈	1.8, 3, 5 µm	110 Å	+	14%	L1	340 m²/g	1.0‒9.0	N/A
Nucleodur^® C₁₈ HTec	C₁₈	1.8, 3, 5, 7, 10 µm	110 Å	+ (Polar)	18%	L1	340 m²/g	1.0‒11.0	N/A
Nucleodur^® C₁₈ ec	C₁₈	3, 5, 7,... µm 5 µm	110 Å 300 Å	+	17% 4%	L1	340 m²/g 100 m²/g	1.0‒9.0	N/A
Nucleodur^® C₁₈ PAH	C₁₈	1.8, 3 µm	110 Å	N/A	N/A	L1	340 m²/g	N/A	N/A
Nucleodur^® C₈ Gravity	C₈	1.8, 3, 5 µm	110 Å	+	11%	L7	340 m²/g	1.0‒11.0	N/A
Nucleodur^® C₈ ec	C₈	3, 5 µm	110 Å	+	10.5%	L7	340 m²/g	1.0‒9.0	N/A
Nucleodur^® C₄ ec	C₄	5 µm	300 Å	+	2.5	L26	100 m²/g	1.0‒9.0	N/A
Nucleodur^® Phenyl-Hexyl	Phenylhexyl	1.8, 3, 5 µm	110 Å	+	10%	L11	340 m²/g	1.0‒10.0	N/A
Nucleodur^® π²	Biphenylpropyl	3, 5 µm	110 Å	+	17%	L11	340 m²/g	1.0‒10.0	N/A
Nucleodur^® CN/CN-RP	Cyanopropyl	3, 5 µm	110 Å	+	7%	L10	340 m²/g	3.0‒10.0	N/A
Nucleodur^® NH₂/NH₂-RP	Aminopropyl	3, 5, 7 µm	110 Å	-	2.5%	L8	340 m²/g	1.0‒8.0	N/A
Nucleodur^® PFP	Pentafluorophenylpropyl	1.8, 3, 5 µm	110 Å	+	8%	L43	340 m²/g	1.0‒9.0	N/A
Nucleodur^® Sphinx RP	Mixed Mode Propylphenyl + C₁₈	1.8, 3, 5 µm	110 Å	+	15%	L1 L11	340 m²/g	1.0‒10.0	N/A
Nucleodur^® PolarTec	Polar embedded C₁₈	1.8, 3, 5 µm	110 Å	+	17%	L1 L60	340 m²/g	1.0‒9.0	N/A
Nucleodur^® HILIC	Ammonium-Sulfonsäure	1.8, 3, 5 µm	110 Å	-	7%	N/A	340 m²/g	2.0‒8.5	N/A
Nucleodur^® SiOH	-	3, 5, 7, 10,... µm	110 Å	-	-	L3	340 m²/g	2.0‒8.0	N/A

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