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Inertsil Hybrid-C18
Inertsil Hybrid-C18 consist of a hybrid material from GL-Sciences. This hybrid material enables a wide pH range of the columns from 1.0-12.0. At the same time, these phases can be used at up to 60 °C (pH 11.0-12.0) or 80 °C (pH 1.0-10.0). By using them at high pH values, bases can be analysed in a neutral state, resulting in more symmetrical peaks. In addition to this high pH stability, this phase can also be used with 100% aqueous mobile phases.
Product Line
- Inertsil
- Inertsil Hybrid-C18
- InertSustain
- InertSustain Swift
- InertCap
- InertSep
- Titansphere
- LD249 Gas Leak Detector
- GF-1010 Digital Gas Flow Meter
- Bioptic
- GL Sciences-HayeSep
- GL Sciences-Porapak
- GL Sciences-TC
- GL Sciences-Tenax
- GL Sciences-Unibeads
- InertCore
- InertSep WAX FF/GCB
- InertSphere
- MonoCap
- MonoFas
- MonoSpin
- MonoTrap
- OPTIC
- ProteoSil
- SYPRON
Technical Data
| Phase | Modification | Particle size | Pore size | Surface area | Carbon content | Endcapped | USP | pH range | Temperature range |
| Inertsil Hybrid C18 | Hybrid C18 | 1.7, 3.5, 5 µm | 165 Å | 185 m²/g | 15 %C | + | L1 | 1.0 - 12.0 | 80°C (pH 1.0-10.0) 60°C (pH 11.0-12.0) |
What characterises the Inertsil Hybrid-C18?
- high pH stability
- higher stability compared to other hybrid or pH-stable phases
- High lot-to-lot reproducibility for all particle sizes
When will you benefit from the Inertsil Hybrid C18?
Change in selectivity due to the pH value
Peak identities
1. epinastine 2. cetirizine 3. fexofenadine 4. chlorpheniramine 5. ketotifen 6. hydroxyzine 7. triprolidine 8. azelastine 9. loratadine 10. homochlorocyclizine 11. clemastine
Applications
Separation of antihistamines
Peak identities
1. epinastine 2. chlorpheniramine 3. fexofenadine 4. triprolidine 5. ketotifen 6. cetirizine 7. azelastine 8. hydroxyzine 9. homochlorocyclizine 10. clemastine 11. loratadine
Test conditions
Column: Inertsil Hybrid-C18 150x2.1 mm, 3.5 µm
Analysis of antidepressants
Peak identities
1. nortriptyline 2. imipramine 3. amitriptyline 4. sertraline 5. clomipramine 6. mianseline
Test conditions
Column: Inertsil Hybrid-C18 150x2.1 mm, 3.5 µm
Downloads
Brochures
GL Sciences Inertsil Hybrid C18 Brochure
The right column for you - we will be happy to support you individually
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