Checkout using your account
Checkout as a new customer
Creating an account has many benefits:
- See order and shipping status
- Track order history
- Check out faster
Inertsil Hybrid-C18
Inertsil Hybrid-C18 HPLC columns are silica-based chromatography columns with a hybrid organic-inorganic bonding technology from the manufacturer GL Sciences, Japan. The special hybrid silica material enables exceptional stability of the HPLC columns in the wide pH range of 1.0 - 12.0. High pH values are particularly suitable for bases in analysis, as these can be analysed in a neutral state with more symmetrical peaks.
Advantages at a glance:
- pH range 1-12 for acidic and alkaline conditions
- Excellent reproducibility from batch to batch
- Compatible with LC/MS, LC/MS/MS and high pressure LC systems
- High durability and long lifetime, even at basic pH
- Compatible with 100% aqueous mobile phases
- Hardware: Stainless steel (SS) and biocompatible PEEK
Applications: Guanine-based antiviral analytes (acyclovir), nucleoside-based antiviral drugs (ribavirin), macrolide antibiotics (azithromycin), antihistamines (azelastine, loratadine), antidepressants (sertraline, amitriptyline)
Product Line
- Inertsil
- Inertsil Hybrid-C18
- InertSustain
- InertSustain Swift
- InertCap
- InertSep
- Titansphere
- LD249 Gas Leak Detector
- GF-1010 Digital Gas Flow Meter
- Bioptic
- GL Sciences-HayeSep
- GL Sciences-Porapak
- GL Sciences-TC
- GL Sciences-Tenax
- GL Sciences-Unibeads
- InertCore
- InertSep WAX FF/GCB
- InertSphere
- MonoCap
- MonoFas
- MonoSpin
- MonoTrap
- OPTIC
- ProteoSil
- SYPRON
Technical Data
| Phase | Modification | Particle size | Pore size | Surface area | Carbon content | Endcapped | USP | pH range | Temperature range |
| Inertsil Hybrid C18 | Hybrid C18 | 1.7, 3.5, 5 µm | 165 Å | 185 m²/g | 15 %C | + | L1 | 1.0 - 12.0 | 80°C (pH 1.0-10.0) 60°C (pH 11.0-12.0) |
What characterises the Inertsil Hybrid-C18?
- high pH stability
- higher stability compared to other hybrid or pH-stable phases
- High lot-to-lot reproducibility for all particle sizes
When will you benefit from the Inertsil Hybrid C18?
Change in selectivity due to the pH value
Peak identities
1. epinastine 2. cetirizine 3. fexofenadine 4. chlorpheniramine 5. ketotifen 6. hydroxyzine 7. triprolidine 8. azelastine 9. loratadine 10. homochlorocyclizine 11. clemastine
Applications
Separation of antihistamines
Peak identities
1. epinastine 2. chlorpheniramine 3. fexofenadine 4. triprolidine 5. ketotifen 6. cetirizine 7. azelastine 8. hydroxyzine 9. homochlorocyclizine 10. clemastine 11. loratadine
Test conditions
Column: Inertsil Hybrid-C18 150x2.1 mm, 3.5 µm
Analysis of antidepressants
Peak identities
1. nortriptyline 2. imipramine 3. amitriptyline 4. sertraline 5. clomipramine 6. mianseline
Test conditions
Column: Inertsil Hybrid-C18 150x2.1 mm, 3.5 µm
Downloads
Brochures
GL Sciences Inertsil Hybrid C18 Brochure
The right column for you - we will be happy to support you individually
Competent consultants are always at your side. Write a message to our consultants, we will get back to you and give you individual support.
You will find:
Application support
Availability and delivery times
Price information with individual conditions
Certificates of analysis, MSDS, data sheets
Write us a message and we will get back to you as soon as possible.