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Chiral Technologies - Daicel / Chiralpak

Chiralpak

Logo of the manufacturer Daicel - Chiral

The Chiralpak® product range from the manufacturer Chiral Technologies (Daicel) includes many different HPLC phases for enantiomer separation. There are both "coated" and "immobilised" polysaccharide modifications. The immobilised modifications have the advantage that any organic solvent can be used. With coated phases, some organic solvents can alter or completely destroy the modification. This means that the immobilised phases also enable further method developments that were previously not possible.

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Items 431-440 of 1011

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Chiralpak IF 20µm 500x50mm HPLC Column
CT-86256
Chiralpak IF 20µm 300x4.6mm HPLC Column
CT-86226
Chiralpak IF 20µm 250x4.6mm HPLC Column
CT-86225
Chiralpak IF 20µm 150x4.6mm HPLC Column
CT-86224
Chiralpak IF 20µm 100x4.6mm HPLC Column
CT-86223
Chiralpak IF 10µm Bulk Media 1000g
CT-8600E
Chiralpak IE-3 3µm 150x2.1mm SFC Column
CT-85S84
€1,860.00
Chiralpak IE-3 3µm 100x2.1mm SFC Column
CT-85S83
€1,490.00
Chiralpak IE-3 3µm 50x2.1mm SFC Column
CT-85S82
€1,090.00
Chiralpak IE-10 10µm 250x30mm SFC Column
CT-85G75
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Items 431-440 of 1011

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Technical Data

Phase name

Chiral selector

Particle size

USP

pH range

Tmax

Chiralpak® AD

Amylose-tris-(3,5-dimethylphenylcarbamate)

3, 5, 10 µm

L51

2.0-9.0

40 °C

Chiralpak® AS

Amylose-tris-(S)-α-methylbenzylcarbamate

3, 5, 10 µm

L90

2.0-9.0

40 °C

Chiralpak® AY

Amylose-tris-(5-chloro-2-methylphenylcarbamate)

3, 5, 10 µm

N/A

2.0-9.0

40 °C

Chiralpak® AZ

Amylose-tris-(3-chloro-4-methylphenylcarbamate)

3, 5, 10 µm

N/A

2.0-7.0

40 °C

Chiralpak® IA

Amylose-tris-(3,5-dimethylphenylcarbamate)

1.6, 3, 5, 10 µm

L99

2.0-9.0

40 °C

Chiralpak® IB

Cellulose-tris-(3,5-dimethylphenylcarbamate)

1.6, 3, 5, 10 µm

N/A

2.0-9.0

40 °C

Chiralpak® IC

Cellulose-tris-(3,5-dichlorophenylcarbamate)

1.6, 3, 5, 10 µm

N/A

2.0-9.0

40 °C

Chiralpak® ID

Amylose-tris-(3-chlorophenylcarbamate)

3, 5, 10 µm

N/A

2.0-9.0

40 °C

Chiralpak® IE

Amylose-tris-(3,5-dichlorophenylcarbamate)

3, 5, 10 µm

N/A

2.0-9.0

40 °C

Chiralpak® IF

Amylose-tris-(3-chloro-4-methylphenylcarbamate)

3, 5, 10 µm

N/A

2.0-9.0

40 °C

Chiralpak® IG

Amylose-tris-(3-chloro-5-methylphenylcarbamate)

1.6, 3, 5, 10 µm

N/A

2.0-9.0

40 °C

Chiralpak® IH

Amylose-tris-((S)-α-methylbenzylcarbamate)

1.6, 3, 5 µm

N/A

2.0-9.0

40 °C

Chiralpak® Zwix (+)

Quinine combined with(S,S)-trans-Aminocyclo-hexanesulfonic acid

3 µm

N/A

N/A

45 °C

Chiralpak® Zwix (-)

Quinidine combined with(R,R)-trans-aminocyclo-hexanesulfonic acid

3 µm

N/A

N/A

45 °C

Chiralpak® AGP

a1-acid glycoprotein

5 µm

L41

4.0-7.0

30 °C

Chiralpak® CBH

Cellobiohydrolase

5 µm

N/A

4.0-7.0

30 °C

Chiralpak® HSA

Human serum albumin

5 µm

N/A

5.0-7.0

30 °C

Chiralpak® QN-AX

9-O-(tert-butylcarbamoyl) quinine

5 µm

N/A

2.0-8.0

40 °C

Chiralpak® QD-AX

9-O-(tert-butylcarbamoyl) quinidine

5 µm

N/A

2.0-8.0

40 °C

Chiralpak® MA(+)

N,N-Dioctyl-L-alanine- Cu(II)-complex

3 µm

N/A

N/A

40 °C

Chiralpak® WH

L-proline - Cu(II)-complex

10 µm

L32

N/A

50 °C

  • Chiralpak® immobilised phases (IA, IB, IC, ID, IE, IF and IH) are a newer generation of polysaccharide phases, in which the amylose or cellulose chiral selector has been immobilised on to a wide pore silica matrix. This results in a higher solvent stability compared to the traditional coated phases, which simplifies the method development. Columns for SFC are available.
  • Chiralpak® AD, AS, AY and AZ are coated amylose phases and the predecessors to immobilised phases. These materials have limited solvent stability, compared to the newer immobilised phases, due to the solubility of the polymer coating in certain solvents. Chiralpak® AD and AS phases are well-established phases that are complemented by the newer AY and AZ phases through their alternative selectivity. Columns for SFC are available.
  • Chiralpak® Zwix (+) and Zwix (‒) are immobilised zwitterionic stationary phases incorporating both anion- and cation-exchange functional groups. Chiralpak® Zwix phases exhibit stereoselectivity for zwitterionic compounds, e.g. underivatised amino acids or peptides.
  • Chiralpak® AGP, CBH, and HSA are protein-based stationary phases in which the protein is immobilised on to porous spherical silica particles. These columns function in reversed-phase mode, using buffer with low organic content and at moderate pH value.
  • Chiralpak® QN-AX and QD-AX are chiral stationary phases for anion exchange chromatography. These are ideal for the separation of chiral acids.
  • Chiralpak® MA (+) and WH are chiral stationary phases for ligand exchange chromatography. Chiralpak® MA (+) uses a proline derivative as chiral selector which is covalently bound to silica particles. Chiralpak® WH uses a N,N-Dioctyl-L-alanine as chiral selector which is coated to silica particles. They are used in conjunction with an aqueous CuSO4 eluent and are useful for the separation of amino acids and their derivatives.

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