InertSustainBio C18 1.9µm 4.6 x 50mm (U)HPLC Column

The InertSustainBio C18 HPLC column 50x4.6mm, 1.9µm, is based on an octadecylsilyl phase (also known as ODS, RP-18, C18) on high-purity ES silica gel with a pore size of 200 Å for reverse-phase chromatography. Thanks to the large pore structure, peptides, oligonucleotides, and other larger biomolecules can penetrate the stationary phase more effectively, in addition to smaller molecules. The highly inert packing in steel-coated PEEK hardware reduces unwanted adsorption and promotes symmetrical peaks for metal-sensitive or delicate analytes. InertSustainBio C18 is primarily used for bioanalytical HPLC and UHPLC methods that require broad molecular size coverage, good peak shapes, and LC/MS-compatible operating conditions.

Features and Benefits

• Bio-LC Series for RP-HPLC and UHPLC
• High-purity silica with a controlled surface
• High inertness and good peak shapes
• Low adsorption of sensitive analytes
• Suitable for LC/MS-based bioanalytics

Additional Information

The InertSustainBio series is designed for bioanalytical reverse-phase methods in which undesirable interactions with the packing material or hardware can affect peak shape, recovery, and reproducibility. The combination of high-purity silica, a controlled surface, and biocompatible hardware supports robust HPLC and UHPLC methods for peptides, proteins, oligonucleotides, and related bioanalytical compounds. For effective column protection, a precolumn cartridge or precolumn with the same modification, appropriate particle size, and suitable ID should be used whenever possible.

Legal Information

InertSustainBio is a registered trademark of the manufacturer GL Sciences Inc., Tokyo, Japan.