Inertsil ODS 5µm, HPLC-Column 250x1.5mm HPLC Column

The Inertsil ODS HPLC column 250x1.5mm, 5µm, is the classic octadecyl phase (also known as ODS, RP-18, C18) of the Inertsil series and is used in reverse-phase chromatography. Inertsil ODS is suitable as a general C18 phase for established methods in which the original Inertsil ODS selectivity is to be maintained. The phase offers classic hydrophobic retention and is particularly relevant for method maintenance, comparative measurements, and existing routine procedures. Typical applications include routine pharmaceutical and chemical analysis, environmental analysis, and standard RP-HPLC separations of nonpolar to moderately polar compounds.

Performance Characteristics and Benefits

• High-purity silica
• Controlled pore structure and reproducible surface
• High inertness due to reduced silanol and metal activity
• Excellent peak shapes for acidic, neutral, and basic analytes
• Reliable reproducibility for routine analysis

Additional Notes

The Inertsil series is based on a high-purity, spherical silica matrix whose pore structure, particle size distribution, and surface are carefully controlled during production. Low metal contamination and careful surface treatment reduce the activity of free silanol groups. This minimizes undesirable secondary interactions—particularly tailing and adsorption with basic or chelating analytes—and promotes stable retention times. This reproducible silica matrix forms the basis for the various Inertsil modifications and ensures reliable selectivities across the series. Appropriate Inertsil pre-column cartridges should be used to protect the analytical packing bed from particles and the sample matrix and to extend column lifespan.

Legal Notices

Inertsil is a registered trademark of the manufacturer GL Sciences Inc., Tokyo, Japan.